We used Macbooks in our Labs for about 2 years, from 2011 to 2011. Macbooks work best in a 1:1 environment so naturally there were some issues. The biggest problem is lack of ownership and they were not cared for as well as I would have liked.
The most difficult parts of maintaining the lab were keeping the computer lab tidy and ensuring that all the Macbooks were properly charged.
I ended up having to put posters in the room clearly showing how the room should be left a the end of each lesson Staff – Please Leave Computer LABS as Shown (PDF Document)